Famciclovir (FAMVIR®)
نویسنده
چکیده
Famciclovir is an antiviral with efficacy and safety comparable to aciclovir, but famciclovir's more favorable pharmacokinetic profile enables a less frequent dosing regimen. Future trials will likely determine famciclovir's role in the suppression of HBV.
منابع مشابه
Famiciclovir therapy (famvir) for herpes simplex and herpes zoster infections.
Genital herpes simplex and herpes zoster infections are common afflictions that are associated with significant morbidity and a decreased quality of life. Famciclovir (Famvir, Novartis) is an orally administered prodrug of the antiviral agent penciclovir. Its unique pharmacokinetic profile makes it an efficacious, convenient and well-tolerated alternative to the traditionally prescribed acyclov...
متن کاملCombination treatment with famciclovir and a topical corticosteroid gel versus famciclovir alone for experimental ultraviolet radiation-induced herpes simplex labialis: a pilot study.
To investigate the efficacy of corticosteroids for the treatment of herpes labialis, we compared famciclovir (Famvir, 500 mg 3x/day po [per os] for 5 days) and topical fluocinonide (0.05% Lidex Gel 3x/day for 5 days) with famciclovir and topical vehicle control for experimental ultraviolet radiation-induced herpetic recurrences. We irradiated 49 volunteers, and 29 (60%) of 48 developed signs or...
متن کاملUse of famciclovir for the treatment of endotheliotrophic herpesvirus infections in Asian elephants (Elephas maximus).
Two juvenile Asian elephants (Elephas maximus) presented with an acute onset of facial edema and lethargy. Examination of the oral cavity of each animal revealed cyanosis of the tip and distal margins of the tongue suggestive of endothelial inclusion body disease (EIBD) of elephants. Whole-blood samples were obtained, and polymerase chain reaction tests confirmed the presence of elephant herpes...
متن کاملDOSAGE AND ADMINISTRATION 2.1 Dosing Recommendation in Immunocompetent Adult Patients 2.2 Dosing Recommendation in HIV-Infected Adult Patients 2.3 Dosing Recommendation in Patients with Renal Impairment 3 DOSAGE FORMS AND STRENGTHS
FAMVIR, a prodrug of penciclovir, is a nucleoside analogue DNA polymerase inhibitor indicated for: Immunocompetent Adult Patients (1.1) • Herpes labialis (cold sores) • Genital herpes o Treatment of recurrent episodes o Suppressive therapy of recurrent episodes • Herpes zoster (shingles) HIV-Infected Adult Patients (1.2) • Treatment of recurrent episodes of orolabial or genital herpes Limitatio...
متن کاملFamciclovir suppression of asymptomatic and symptomatic recurrent anogenital herpes simplex virus shedding in women: a randomized, double-blind, double-dummy, placebo-controlled, parallel-group, single-center trial.
Genital herpes is most often transmitted while the patient is asymptomatic, presumably during episodes of viral shedding. To determine whether famciclovir is effective in reducing asymptomatic shedding, women with frequent, recurrent genital outbreaks were enrolled in a randomized, double-blind, double-dummy, placebo-controlled, parallel-group, 112-day trial of suppressive treatment with famcic...
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عنوان ژورنال:
- Infectious Diseases in Obstetrics and Gynecology
دوره 5 شماره
صفحات -
تاریخ انتشار 1997